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DIA proteomics on mouse tissue to investigate the GAPDH redox switch

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NIAID Data Ecosystem2026-05-01 收录
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The glycolytic enzyme GAPDH is equipped with a redox switch that rapidly and reversibly inactivates the enzyme in the presence of hydrogen peroxide. The physiological implications of the redox switch were investigated in C57BL/6NTac wildtype and GAPDH(T175A) knock-in mice generated by CRISPR/Cas9 genome editing.

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2023-04-10
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