Mutations and FcRn binding affinity of hIgG1 Fc variants.
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Binding affinity (KD) of IgG1 and v1 to mFcRn at pH 7.0 and pH 6.0, binding affinity (KD) of IgG1, v2-v6 and v0 to hFcRn at pH 7.0 and pH 6.0, and mutations introduced in the Fc region are shown. Mutation sites in the Fc region are described in EU numbering. NT, not tested.
创建时间：
2015-12-02
