Pleiotropy analysis using Egger regression of unpruned single-trait MR.

Lipid association statistics are from MVP, and the outcome trait was risk for all BC. Exposure: lipid trait used as the exposure; Egger intercept: intercept estimate from Egger regression; SE: standard error of intercept estimate; P: P-value of intercept estimate. BC, breast cancer; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MR, Mendelian randomization; MVP, Million Veteran Program; TC, total cholesterol; TG, triglyceride. (XLSX)