DNA-damage induced differentiation of leukemic cells as an anti-cancer barrier
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=a67abb9ae4e4468b0480a60cc6ddeab6
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资源简介：
Here we show that the histone methyltransferase MLL4 (Kmt2d) is required for stem cell activity and an aggressive form of acute myeloid leukemia (AML) harboring the MLL-AF9 oncogene. MLL4 exerts its function by regulating transcriptional programs associated with the anti-oxidant response.
提供机构：
University of Pennsylvania
创建时间：
2022-02-20
