Overexpressed SNCA in differentiated SH-SY5Y neuroblastoma cells
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2022-03-10
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Gene expression of hiPSC-derived DA Neurons harboring SNCA A53T mutation or genome Corrected and hESC-derived WT DA Neurons and SNCA A53T mutation introduced Corrected. Gene expression of hiPSC-derived DA Neurons harboring SNCA A53T mutation or genome Corrected and hESC-derived WT DA Neurons and SNCA A53T mutation introduced Corrected
A53T mutant human DA neurons or their isogenic control counterparts were differentiated to DA-Neurons for 35 days. Gene expression profile was analysed to assess the effect of the genetype on gene exp
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Figure8.xlsx
C.R infection aggravated the MPTP-induced nigrostriatal system lesions
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Data source of Microphysiological engineering of the capillary interface of substantia nigra dopaminergic neurons to study vascular alterations in Parkinson’s Disease
Parkinson’s disease involves not only α-synuclein pathology but also significant vascular dysfunction that traditional models fail to capture. Using organ-on-a-chip technology and vasculogenic self-as
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Behavioral Characterization of A53T Mice Reveals Early and Late Stage Deficits Related to Parkinson’s Disease
Parkinson's disease (PD) pathology is characterized by the formation of intra-neuronal inclusions called Lewy bodies, which are comprised of alpha-synuclein (α-syn). Duplication, triplication or genet
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Amphotericin B Inhibits the Generation of the Scrapie Isoform of the Prion Protein in Infected Cultures
Transmissible spongiform encephalopathies form a group of fatal neurodegenerative disorders that have the unique property of being infectious, sporadic, or genetic in origin. Although some doubts abou
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