Transmission of homogenous GSS-102L prions to wild type FVB mice or transgenic mice expressing PrP 102L or wild type human PrP.
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https://figshare.com/articles/dataset/_Transmission_of_homogenous_GSS_102L_prions_to_wild_type_FVB_mice_or_transgenic_mice_expressing_PrP_102L_or_wild_type_human_PrP_/1472563
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IHC = immunohistochemistry; IB = immunoblotting. Tg35c and Tg152c are congenic on FVB/N genetic background.
* Three IPD P102L patient brain isolates were passaged in 102LL Tg27 transgenic mice to generate GSS-102L prions. Details of these primary transmission are described in reference [33].
† All samples were analysed by both IB and IHC using monoclonal antibodies ICSM 18 and ICSM 35. In 102LL Tg27 tissues ICSM 35 serves as a control to define non-specific background.
‡ Positive either by clinical signs, immunoblotting and/or immunohistochemistry.
# All samples were positive for ICSM 18 but negative for ICSM 35.
§ All samples were negative for both ICSM 18 and ICSM 35.
Transmission of homogenous GSS-102L prions to wild type FVB mice or transgenic mice expressing PrP 102L or wild type human PrP.
创建时间：
2015-07-02
