Although classical single cell RNA analysis is a very powerful tool, it nevertheless has several drawbacks. To overcome these two disadvantages, the cell hashing technique seems interesting. In this w

NIAID Data Ecosystem10

RNA sequestration in P-bodies sustains myeloid leukaemia

急性髓系白血病

P-bodyRNA隔离

Post-transcriptional mechanisms are fundamental safeguards of progenitor cell identity and are often dysregulated in cancer. Here, we identified regulators of P-bodies as crucial vulnerabilities in ac

NIAID Data Ecosystem00

Clinical and molecular characteristics of the 70 patients with AML at diagnosis included in the study.

急性髓系白血病

肿瘤基因组学

Clinical and molecular characteristics of the 70 patients with AML at diagnosis included in the study.

Figshare2015-12-02 更新10

Data_Sheet_2_Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells.docx

急性髓系白血病

苦味受体信号通路

The contribution of cell-extrinsic factors in Acute Myeloid Leukemia (AML) generation and persistence has gained interest. Bitter taste receptors (TAS2Rs) are G protein-coupled receptors known for the

NIAID Data Ecosystem10

AML subtypes, tumor markers and cytogenetic abnormalities.

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