Influence of Coronary Artery Disease on Cardiolocomotor Coupling during Walking

We examined the mechanisms involved in coupling between cardiac and locomotor rhythms (CLC) in patients with coronary artery disease. This preliminary study enrolled eight outpatients with coronary artery disease (CAD group) and eight healthy individuals (control group) who underwent cardiopulmonary exercise testing involving a cycle ergometer ramp protocol and treadmill walk test to record CLC strength (R2 value). The CAD group showed a significantly higher incidence of CLC intensity and lower peak oxygen uptake and oxygen uptake at the anaerobic threshold compared with the control group.