Structure of EED bound to EEDi-6068
收藏Protein Data Bank Japan2024-04-03 更新2026-04-19 收录
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Structure of EED bound to EEDi-6068 Descriptor: (9aP,12aR)-4-(2,2-difluoropropyl)-12-{[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]amino}-7-(trifluoromethyl)-4,5-dihydro-3H-2,4,8,11,12a-pentaazabenzo[4,5]cycloocta[1,2,3-cd]inden-3-one, FORMIC ACID, Polycomb protein EED Authors: Petrunak, E, Stuckey, J. Deposit date: 2021-05-11 Release date: 2021-10-20 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of EEDi-5273 as an Exceptionally Potent and Orally Efficacious EED Inhibitor Capable of Achieving Complete and Persistent Tumor Regression. J.Med.Chem., 64, 2021
创建时间：
2021-05-11
