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Eukaryotic initiation factor 5A2 regulates expression of antiviral genes

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NIAID Data Ecosystem2026-03-14 收录
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Using ribosome profiling and RNA-Sequencing, we reveal that eIF5A2 is functionally distinct from eIF5A1 and does not regulate transcript-specific or global protein synthesis. Instead, eIF5A2 knockout leads to decreased intrinsic antiviral gene expression. SW480 cells were grown in complete media for a day before harvesting.

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2022-10-31
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