Nicotinamide Riboside-Conditioned Microbiota Deflects High-Fat Diet-Induced Weight Gain in Mice

In this study, we sought to investigate the hypothesis that dietary nicotinamide riboside supplementation alters the murine gut microbiome to mediate diet-induced weight gain deflection. To test this hypothesis, we fed C57BL6J males a high-fat diet supplemented with or without NR and then performed a fecal material transplant into naive recipients.