The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293472
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Experimental atherosclerosis was established by feeding Apoe KO mice a western diet(WD) for 14 weeks and experimental cerebral ischemia was established by bilateral carotid artery stenosis (BCAS). RNA-seq was perfomed to investigate the potential gene regulation of AS-Exos-dependent changes of microglia in the corpus callosum after BCAS. Transcriptional profiles of microglia sorted from Sham mice, BCAS mice, BCAS mice treated with ND-Exos, and BCAS mice treated with WD-Exos.
创建时间：
2025-04-30
