In-Depth Plasma Proteomics Identifies Metabolic Dysregulation and Chemokine Levels in Atopic Dermatitis

Despite the availability of multiple evaluation indices, the current assessment framework for AD severity is heterogeneous and highly dependent on subjective judgment, leading to considerable inter-individual variability. As a result, objective criteria for disease stratification and timely therapeutic intervention are lacking. we focused on proteins involved in two key biological processes closely associated with AD pathogenesis: metabolism and inflammation.