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资源简介:
RNA-seq and WGBS-seq of muscle stem cells isolated from TET2-KO and WT sample
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创建时间:
2022-01-12
相关数据集
TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.. Mus musculus
Dioxygenases of the TET family impact genome functions by converting 5-methylcytosine in DNA to 5-hydroxymethylcytosine (5hmC), but their contribution to differentiation and function of immune cells i
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Role of Tet1 in genomic imprinting erasure [RNA-seq]
Genomic imprinting is an allele-specific gene expression system important for mammalian development and function. The molecular basis of genomic imprinting is allele-specific DNA methylation 2. While
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TET2-mediated deprogramming of breast cancer cells
Methylation and demethylation of cytosines in DNA are believed to act as keystones of cell-specific gene expression through controlling chromatin structure and accessibility to transcription factors.
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TET2 deficiency subverts tumor immunity [model 3]. TET2 deficiency subverts tumor immunity [model 3]
To investigate the function of TET2 in the development of acute myeloid leukemia (AML), we performed gene expression profiling analysis using data obtained from RNA-seq of AML cells carrying Tet2+/+ v
NIAID Data Ecosystem40
TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells [RNA-Seq]
The epigenetic regulator TET2 is frequently mutated in hematological diseases. Mutations have been shown to arise in hematopoietic stem cells early in disease development, lead to altered DNA methylat
NIAID Data Ecosystem30



