five

BTK IN COMPLEX WITH GDC-0834

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Protein Data Bank Japan2024-05-22 更新2026-03-21 收录
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BTK IN COMPLEX WITH GDC-0834 Descriptor: 1,2-ETHANEDIOL, GLYCEROL, N-{3-[6-({4-[(2R)-1,4-dimethyl-3-oxopiperazin-2-yl]phenyl}amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl]-2-methylphenyl }-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide, ... Authors: Gardberg, A.S. Deposit date: 2016-09-20 Release date: 2017-05-24 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling. Mol. Pharmacol., 91, 2017
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2016-09-20
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