Crystal Structure of Human Dipeptidyl Peptidase I (Cathepsin C): Exclusion Domain Added to an Endopeptidase Framework Creates the Machine for Activation of Granular Serine Proteases

Crystal Structure of Human Dipeptidyl Peptidase I (Cathepsin C): Exclusion Domain Added to an Endopeptidase Framework Creates the Machine for Activation of Granular Serine Proteases Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SULFATE ION, ... Authors: Turk, D, Janjic, V, Stern, I, Podobnik, M, Lamba, D, Dahl, S.W, Lauritzen, C, Pedersen, J, Turk, V, Turk, B. Deposit date: 2001-10-02 Release date: 2002-04-02 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases. EMBO J., 20, 2001人类二肽基肽酶I（Cathepsin C，组织蛋白酶C）的晶体结构：结合至内肽酶骨架的排除结构域构建了颗粒丝氨酸蛋白酶的激活机制。 配体描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、氯离子（CHLORIDE ION）、硫酸根离子（SULFATE ION）等。 作者：Turk, D、Janjic, V、Stern, I、Podobnik, M、Lamba, D、Dahl, S.W、Lauritzen, C、Pedersen, J、Turk, V、Turk, B。 提交日期：2001-10-02。 发布日期：2002-04-02。 最后修改日期：2024-10-30。 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.15埃（2.15 Å）。 引用文献：Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases. EMBO J., 20, 2001