Crystal structure of ERK2 with an allosteric inhibitor 2

Crystal structure of ERK2 with an allosteric inhibitor 2 Descriptor: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... Authors: Yoshida, M, Kinoshita, T. Deposit date: 2022-03-03 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural basis for producing allosteric ERK2 inhibitors To Be PublishedERK2结合变构抑制剂2的晶体结构 描述物：(2R,3R,4S,5R)-2-(4-氨基-5-碘-7H-吡咯并[2,3-d]嘧啶-7-基)-5-(羟甲基)四氢呋喃-3,4-二醇、2-[双(2-羟乙基)氨基]-2-(羟甲基)丙烷-1,3-二醇、甘油…… 作者：Yoshida, M、Kinoshita, T 沉积日期：2022-03-03 发布日期：2023-03-08 最后修改日期：2023-11-29 检测方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.98埃（Å） 引用文献：《变构ERK2抑制剂研发的结构基础》（待发表）