Microbiomes of zebrafish with intestinal neoplasms. zebrafish metagenome

Intestinal neoplasms are common in zebrafish (Danio rerio) research facilities, and there is evidence that they can be transmitted among individuals. We performed five transmission experiments by exposure of naıve fish to affected donor fish by cohabitation or exposure to tank effluent water. We characterized the intestinal bacterial communities associated with both exposed and non-exposed zebrafish by 16S amplicon sequencing to investigate a possible link between disease prevalence and microbiome composition.