The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with avian receptor analog 3'SLNLN

The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with avian receptor analog 3'SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin Authors: Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. Deposit date: 2013-07-07 Release date: 2013-11-06 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.798 Å) Cite: Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013

禽源H7N9流感病毒（A/Anhui/1/2013）采用H3编号系统的血凝素（hemagglutinin）L226Q突变体，与禽类受体类似物3'SLNLN形成复合物的晶体结构。配体结构描述：2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖、N-乙酰-α-神经氨酸-(2→3)-β-D-吡喃半乳糖-(1→4)-2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖（即3'SLNLN）。相关组分：血凝素。作者：Shi Y、Zhang W、Wang F、Qi J、Song H、Wu Y、Gao F、Zhang Y、Fan Z、Gong W、Wang D、Shu Y、Wang Y、Yan J、Gao G.F.。提交日期：2013-07-07；发布日期：2013-11-06；最后修改日期：2024-11-06。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.798 Å）。引用文献：《人感染H7N9流感病毒血凝素的结构与受体结合特性》，发表于《科学》（Science）342卷，2013年。