Human Carbonic Anhydrase II bound tert-butyl (3-(4-(3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propoxy)butoxy)propyl)carbamate

Human Carbonic Anhydrase II bound tert-butyl (3-(4-(3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propoxy)butoxy)propyl)carbamate Descriptor: Carbonic anhydrase 2, MERCURIBENZOIC ACID, N-(3-{4-[3-({2-[(3R)-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}amino)propoxy]butoxy}propyl)-4-sulfamoylbenzamide, ... Authors: Kohlbrand, A.J, O'Herin, C.B. Deposit date: 2022-10-25 Release date: 2023-02-22 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Development of Human Carbonic Anhydrase II Heterobifunctional Degraders. J.Med.Chem., 2023人类碳酸酐酶II（Human Carbonic Anhydrase II）结合(3-(4-(3-((2-(2,6-二氧代哌啶-3-基)-1,3-二氧代异吲哚啉-4-基)氨基)丙氧基)丁氧基)丙基)氨基甲酸叔丁酯。描述符：碳酸酐酶2、汞苯甲酸（MERCURIBENZOIC ACID）、N-(3-{4-[3-({2-[(3R)-2,6-二氧代哌啶-3-基]-1,3-二氧代-2,3-二氢-1H-异吲哚-4-基}氨基)丙氧基]丁氧基}丙基)-4-氨磺酰苯甲酰胺…… 作者：Kohlbrand, A.J.、O'Herin, C.B.。提交日期：2022-10-25；发布日期：2023-02-22；最后修改日期：2023-10-25。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.9埃（Å）。引用文献：《人类碳酸酐酶II异双功能降解剂的开发》，《药物化学杂志（J. Med. Chem.）》，2023年。