Biological and pharmacological properties of the ARVs.
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aNRTI, Nucleoside reverse transcriptase inhibitor; NNRTI, Non-nucleoside reverse transcriptase inhibitor; INI, Integrase inhibitor.bThe in vivo plasma concentration range [36].cThe in vivo cerebrospinal fluid (CSF) concentration range [36].d50% inhibitory concentration range for HIV-1 [36].eCPE, CNS penetration-effectiveness (The scale is from 1 to 4, with 4 being the most favorable CNS penetration-effectiveness) [12].fHighest non-cytotoxic concentrations evaluated in a cell culture system in all cell types (SVG, PFA, PBMC, and MDM cells).
创建时间:
2013-04-16



