The complex structure of Braf V600E kinase domain with a novel Braf inhibitor
收藏Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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The complex structure of Braf V600E kinase domain with a novel Braf inhibitor Descriptor: 5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one, Serine/threonine-protein kinase B-raf Authors: Feng, Y, Peng, H, Zhang, Y, Liu, Y, Wei, M. Deposit date: 2014-08-22 Release date: 2016-02-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.5 Å) Cite: BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers. Mol.Cancer Ther., 14, 2015
创建时间：
2014-08-22
