Protective and nonprotective epitopes from amino termini of M proteins from Australian aboriginal isolates and reference strains of group A streptococci.
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Cysteine residue is added to the C-terminal of peptide for conjugation to tetanus toxoid. Cross-reactive peptides BSA101-28, 20341-19, Y504S1-20 and 88/301-20 inhibitated opsonization activity of the epitope-specific antisera against the homologous isolate, but not non-crossreactive peptide Y530S1-20.
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2000-01-01
