Crystal structure of the TYK2 pseudokinase domain in complex with compound 8
收藏Protein Data Bank Japan2024-10-09 更新2026-04-25 收录
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Crystal structure of the TYK2 pseudokinase domain in complex with compound 8 Descriptor: (8S)-N-cyclopropyl-5-[(2-methoxypyridin-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2 Authors: Toms, A.V, Leit, S, Greenwood, J.R, Carriero, S, Mondal, S, Abel, R, Ashwell, M, Blanchette, H, Boyles, N, Cartwright, M, Collis, A, Feng, S, Ghanakota, P, Harriman, G.C, Hosagrahara, V, Kaila, N, Kapeller, R, Rafi, S, Romero, D.L, Tarantino, P, Timaniya, J, Wester, R.T, Westlin, W, Srivastava, B, Miao, W, Tummino, P, McElwee, J.J, Edmondson, S.D, Massee, C.E. Deposit date: 2023-03-27 Release date: 2023-07-26 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279. J.Med.Chem., 66, 2023
创建时间：
2023-03-27
