Comparison of the transcriptional changes in dorsal root ganglion between paclitaxel and oxaliplatin induced peripheral neuropathic pain in rats

In this study, we screened the differentially expressed genes (DEGs) in dorsal root ganglion between paclitaxel and oxaliplatin induced peripheral neuropathic pain in rats. Overall design: Paclitaxel (2.0 mg/kg dissolved in DMSO and serially diluted in saline, Dalian Meilun Biology Technology Co. Ltd, China) and Oxaliplatin (2.4 mg/kg dissolved in 5.0% glucose solution, Dalian Meilun Biology Technology Co. Ltd., China) was injected intraperitoneally to induce peripheral neuropathic pain.