Crystal structure of His-tagged human thymidylate synthase R175A mutant
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Crystal structure of His-tagged human thymidylate synthase R175A mutant Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase Authors: Pozzi, C, Mangani, S. Deposit date: 2013-05-14 Release date: 2014-05-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase. J.Med.Chem., 58, 2015
创建时间:
2013-05-14



