Discovery of novel biomarkers in renal cell carcinoma
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE92482
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A total of 164 ccRCC patient’s specimens were used for microarray (n=12, tumor and corresponding normal tissue) or pyrosequencing (PSQ) analyses (n=152). From The Cancer Genome Atlas (TCGA) portal, microarray methylation profiles composed of 312 subjects with ccRCC were utilized (159 for gene selection and 153 for prognostic relevance). Using the methylation profiles from our and TCGA, tumor-specific hypermethylated genes were selected, and prognostic relevance of candidate markers were examined with TCGA data set and pyrosequencing analysis data from our ccRCC patients samples. DNA from the 24 samples were hybridised to the Illumina Infinium HumanMethylation450 BeadChip kits
创建时间:
2019-12-16



