Data_Sheet_1_Gestational Age-Specific Complete Blood Count Signatures in Necrotizing Enterocolitis.PDF
收藏frontiersin.figshare.com2023-05-31 更新2025-01-15 收录
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Objective: Necrotizing enterocolitis (NEC) is characterized by peripheral cell abnormalities, yet few studies have analyzed the complete blood count (CBC) specifically by gestational age (GA). Our objective was to describe GA-specific immune abnormalities in NEC through a comprehensive analysis of the CBC differential.Methods: Using a cohort of 246 infants (177 cases, 69 controls) admitted to neonatal intensive care units at a single institution, we retrospectively analyzed CBCs around illness onset in NEC cases compared with controls. Cases included surgical NEC (S-NEC, 34.5%) and medical NEC (M-NEC, 65.5%). Infants were divided into those born at GA
目标：坏死性小肠结肠炎（NEC）以周围细胞异常为特征，然而，鲜有研究针对妊娠年龄（GA）对完整血细胞计数（CBC）进行具体分析。本研究旨在通过对CBC差异的全面分析，描述NEC中GA特异性的免疫异常。方法：利用单一医疗机构新生儿重症监护病房中246名婴儿（病例177例，对照69例）的队列，我们对NEC病例发病时的CBC进行回顾性分析，并与对照进行比较。病例包括手术NEC（S-NEC，占34.5%）和医疗NEC（M-NEC，占65.5%）。婴儿被分为GA
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