Commensal multi drug-resistant ESBL Escherichia coli isolated from live bird market

The threat to world health posed by antimicrobial resistance (AMR) is growing quickly. The primary source of the current AMR crisis in the world is the careless and unregulated use of antibiotics for treatment, prevention, and productivity enhancement. The main bacteria that live in the gut are commensal Escherichia coli, which are thought to be a sign of the antibiotic pressure. Different resistance genes emerge and accumulate in their genomes, along with their mobile genomic content known as plasmids, as they acquire distinct mechanisms against these various classes of therapeutic agents. These resistance genes can spread from contaminated commensal E. coli to any pathogenic strains by horizontal gene transfer. These conditions may contribute to the development of an pathogenic E. Coli or other enteric pathogenic bacteria that are resistant to variety classes of antibiotics, known as a multidrug resistant strain. Extended spectrum beta-lactamase (ESBL) genes are very significant resistant gene against beta-lactam antibiotics. Bacteria that can produce ESBL are likely to harbor a variety of resistance genes. Targeting cefotaxime-resistant bacteria is one way to isolate these ESBL producing isolates. The aim of the study was to identify and archive the distribution of ESBL genes in poultry targeting the cefotaxime-resistant E. coli form common junctions like live bird market.