Human Protein Atlas - Tissue
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This section of the Human Protein Atlas focuses on the expression profiles in human tissues of genes both on the mRNA and protein level. The protein expression data from 44 normal human tissue types is derived from antibody-based protein profiling using conventional and multiplex immunohistochemistry. All underlying images of immunohistochemistry stained normal tissues are available together with knowledge-based annotation of protein expression levels. The protein data covers 15318 genes (76%) for which there are available antibodies. The mRNA expression data is derived from deep sequencing of RNA (RNA-seq) from 256 different normal tissue types.
More information about the specific content and the generation and analysis of the data in the section can be found on the Methods Summary.
Learn about:
protein localization in tissues at a single-cell level
if a gene is enriched in a particular tissue (specificity)
which genes have a similar expression profile across tissues (expression cluster)
本节聚焦于人类蛋白质图谱中,关于人类组织中基因在mRNA及蛋白质层面的表达谱。44种正常人类组织类型的蛋白质表达数据,通过抗体介导的蛋白质分析,采用传统及多重免疫组化技术获得。所有免疫组化染色正常组织的底图及其蛋白质表达水平的知识库注释均一并提供。蛋白质数据涵盖了15318个基因(占76%),对于这些基因,均有相应的抗体可用。mRNA表达数据则来源于256种不同正常组织类型的RNA(RNA-seq)深度测序。关于本节特定内容以及数据的生成和分析方法,可在方法概要中获取更多信息。您可以了解以下内容:
在组织层面的单细胞水平上的蛋白质定位
特定基因在特定组织中的富集程度(特异性)
在组织中具有相似表达谱的基因(表达聚类)
提供机构:
v22.proteinatlas.org



