Microbiome changes accompanying ready-to-use supplemental food efficacy in acute childhood malnutrition

This study aims to identify biological predictors of treatment response to ready-to-use supplemental food (RUSF) in children with moderate and severe acute malnutrition. Using data from a longitudinal birth cohort in rural Pakistan, we analyzed gut microbiome profiles and systemic biomarkers in infants who received RUSF following weight faltering. The goal of this work is to understand how gut health and inflammation influence nutritional recovery, and to inform the development of predictive models for precision nutritional interventions in high-risk pediatric populations.