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Crystal Structure of the first bromodomain of human BRD4 L94C variant in complex with racemic 3,5-dimethylisoxazol ligand

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Protein Data Bank Japan2023-11-29 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8ckf
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Crystal Structure of the first bromodomain of human BRD4 L94C variant in complex with racemic 3,5-dimethylisoxazol ligand Descriptor: 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(~{R})-oxidanyl(pyridin-3-yl)methyl]phenol, 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(~{S})-oxidanyl(pyridin-3-yl)methyl]phenol, Bromodomain-containing protein 4 Authors: Thomas, A.M, McDonough, M.A, Schiedel, M, Conway, S.J. Deposit date: 2023-02-15 Release date: 2023-08-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation. Acs Chem.Biol., 18, 2023
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2023-02-15
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