Additional file 9: Table S1. of Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes

Levels of DNA methylation around the first exons of the UGT1A isoforms. The nine UGT1A isoforms were classified into two groups (hepatic and intestinal types). The levels of DNA methylation at individual CpG sites of the first exons were expressed as β values and separately compared between 18 adult livers and one normal small intestine (NSI) or one normal fetal liver (NLF). The β values colored in red were statistically higher than the median of β values of normal adult livers. The β values colored in blue were statistically lower than the median of β values of normal adult livers. The CpG sites proximal to TSS200 region (except TSS1500 region) were indicated by bold frame. (XLSX 15.2 KB)