Platypus RNA Seq, ChIP-Seq and Hi-C data, plus opossum, mouse and chicken RNA-Seq

Gene dosage imbalance of heteromorphic sex chromosomes (XY or ZW) exists between the sexes, and with the autosomes. Mammalian X chromosome inactivation was long thought to imply a critical need for dosage compensation in vertebrates. However, mRNA abundance measurements that demonstrated sex chromosome transcripts are neither balanced between the sexes or with autosomes in monotreme mammals or birds brought sex chromosome dosage compensation into question. This study examines transcriptomic and proteomic levels of dosage compensation in platypus and chicken compared to mouse, a model eutherian species; and opossum, a model marsupial species. Here we present RNA-Seq data for males and females from platypus fibroblasts, chicken heart and liver, mouse heart and liver and opossum fibroblasts. Also here is data for platypus fibroblast ChIP-Seq in males and females, and Hi-C in males.