Elucidation of the metabolic and transcriptional responses of an oriental herbal medicine, Bangpungtongseong-san, to non-alcoholic fatty liver disease in diet-induced obese mice

We investigated the effect of Bangpungtongseong-san on phenotype characteristics and elucidated anti-obesity mechanism based on RNA-seq transcriptomic profiles in an obesity animal model. Overall design: Total RNA of liver was obtained from high-fat diet and Bangpungtongseong-san (BT) extract added high-fat diet-fed mice and mRNA expression-associated with lipid, and glucose metabolism was measured.