Highly Efficient and Versatile Synthesis of Lactams and N‑Heterocycles via Al(OTf)3‑Catalyzed Cascade Cyclization and Ionic Hydrogenation Reactions
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The discovery and development of an efficient and versatile method for the synthesis of N-substituted lactams is described. Pyrrolindinones, piperidones, and structurally related heterocycles were formed by Al(OTf)3-catalyzed cascade cyclization and ionic hydrogenation reactions of corresponding nitrogen substituted ketoamides in good yields.
创建时间：
2016-02-18
