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H2A.Z acetylation by lincZNF337-AS1 via KAT5 implicated in the transcriptional misregulation in cancer signaling pathway in hepatocellular carcinoma

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA668278
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Background: In eukaryotes, histones and their variants are essential for chromatin structure and function; both play important roles in the regulation of gene transcription as well as development of tumors.Methods: we performed RNA-seq using HCC cells (HepG2) from H2A.Z and H2A.Z knockdown.For further research, we conducted the RIP-seq of H2A.Z acetylation.The above experiment shows the gene expression after H2A.Z knockdown and the target genes regulated by H2A.Z acetylated protein
创建时间:
2020-10-09
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