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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome Descriptor: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-18 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
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2007-05-18
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