Pneumococcal pneumonia in 549 adults: A comparison between patients with pneumonia and empyema (Empyema group) and those with pneumonia without empyema (Pneumonia group).

Unless otherwise indicated, data are reported as number (percentage).*Co-morbidities in the empyema group (n) vs. pneumonia group (n) (some patients had more than one): HIV infection (9 vs. 116), malignant disease (15 vs. 85), chronic liver disease (4 vs. 55), immunosuppressive therapy (11 vs. 78), diabetes (5 vs. 57), chronic pulmonary disease (7 vs. 62), cardiovascular disease (2 vs. 33), chronic rheumatic disease or vasculitis (0 vs. 15), asplenia (1 vs. 3), end stage renal failure (3 vs. 12), transplant recipients (1 vs. 17), cerebrovascular or degenerative brain disease (1 vs. 5).†The most common serotypes in patients of empyema group (68/69 serotyped) were: serotype 1 (25%), 3 (12%), 7F (6%), 5 (4%), 19A (4%), 19F (4%), 23F (4%), 4 (3%), 6A (3%), 6B (3%), 8 (3%), 9V (3%), 18C (3%), 23A (3%) and 22 (3%).The most common serotypes in patients of pneumonia group (472/480 serotyped) were: serotype 1 (12%), 7F (9%), 14 (8%), 19A (8%), 3 (7%), 4 (6%), 9V (5%), 5 (5%), 8 (5%), 12F (4%), 23F (3%), 11A (3%), 18C (3%) and 19F (2%).