Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target [DNA_methylation_array]

NIAID Data Ecosystem2026-05-02 收录

母细胞瘤表观遗传学

DNA甲基化分析

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE260660 数据链接链接失效反馈

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资源简介：

Mouse tumor methylation profiling by MouseMethylation Beadchips (MM285) platform The study utilizes the MouseMethylation Beadchips (MM285) platform, focusing on the epigenetic profiling of mouse tumors. We compare genotypes Elp1HET;Ptch1gRNA to Elp1WT;Ptch1gRNA, and Elp1HET;Ptch1gRNA;p53null to Elp1WT;Ptch1gRNA;p53null, exploring tumor epigenetics and comparion with CNS patient methylation

创建时间：

2025-07-09

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target [DNA_methylation_array]

资源简介：

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