Data and code from: Distinct transmission sites within a synapse for strengthening and homeostasis
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https://datadryad.org/dataset/doi:10.5061/dryad.7pvmcvf3x
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We used patch-clamp electrophysiology from mouse brain slices to record
miniature excitatory postsynaptic currents (mEPSC), evoked EPSCs, and
EPSCs with two-photon glutamate uncaging at single spines (uEPSC) to
determine the synaptic properties in visual cortex layer 2/3 pyramidal
neurons during development from postnatal day (P) 10 until P30. Different
parameters of the synaptic responses, such as amplitude, half-width, and
frequency of mEPSCs were determined. These data and their analysis are
documented in the Excel file Data_for_Figures. We also constructed a
synaptic model to explain our results. The model for silent synapses is
documented in the Excel file SS_simulation. The synaptic model was
developed in MatLab, and the code is included in the file Figure_7_code.
The fitting of the mEPSC amplitude distribution is documented in the file
Figure_4_code.
提供机构:
Dryad
创建时间:
2025-04-07



