High-througput sequence was demonstrated with NovaSeq 6000 (Illumina). First, extracted RNAs were purified by poly(A) capture. Resultant mRNAs were then fragmented and reverse-transcribed into single-

NIAID Data Ecosystem20

RNA-seq gene expression profiling of livers from wild-type male and female mice, and from mice with a Double Knockout (DKO) of Ezh1 and Ezh2.

表观遗传调控

组织基因表达

PolyA-selected RNA isolated from livers of adult male and female mice with a combined loss of EZH1 and EZH2 in hepatocytes was analyzed by RNA-seq. The DKO mouse model used in these analyses is a glob

NIAID Data Ecosystem20

cerebellum and hippocampus - deletor x wt

线粒体疾病模型

组织基因表达

Progressive mitochondrial respiratory chain (RC) deficiency is associated with a wide spectrum of adult-onset degenerative diseases, as well as with normal aging. We have previously generated the Dele

NIAID Data Ecosystem30

Gene expression profile induced by moderate physical exercise in heart left ventricles in rats

运动诱导心脏保护

组织基因表达

Physical exercise training is a known protective factor against cardiovascular morbidity and mortality. Nevertheless, the underlying specific molecular mechanisms still remain uncompletely explored. T

NIAID Data Ecosystem20