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Hypothalamic Microglia Activation is Associated with High Fat Diet-Induced Obesity and Metabolic Dysfunction in Mice

NIAID Data Ecosystem2026-03-13 收录

下丘脑小胶质细胞激活

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数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP363605 数据链接链接失效反馈

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资源简介：

Comparing the effect of high-fat diet and minocycline in mouse PVN. Overall design: PVN bulk RNA profile from adult mouse.

应用场景：

创建时间：

2022-07-08

重症儿童高血糖

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ABSTRACT Objective: This study aimed to study the incidence of stress hyperglycemia in critically ill children and to investigate the etiological basis of the hyperglycemia based on homeostasis mode

NIAID Data Ecosystem80

HFD_VV_AKI_Supplemental Figures

急性肾损伤

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Climate change is increasing Vibrio vulnificus infections, while rising obesity rates heighten vulnerability to severe bacterial infections. Obesity and high-fat diet (HFD) intake promote infla

DataCite Commons2025-07-16 更新70

Metabolic dysfunction is integral to TGFb signaling and tissue fibrosis. Metabolic dysfunction is integral to TGFb signaling and tissue fibrosis

纤维化疾病

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Fibrosis, or the accumulation of extracellular matrix, causes loss of organ function and is a common feature of many chronic diseases. To interrogate core molecular pathways underlying fibrosis, we cr

NIAID Data Ecosystem60

Palmer et al. Nature Communications_2024_Olink_Biochemistry data.xlsx

COVID-19研究

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Our understanding of long-term metabolic dysfunctions in COVID-19 remains unclear due to the lack of animal models. We develop a non-human primate model of metabolic post-acute sequelae of SARS-CoV-2

DataCite Commons2024-04-26 更新80

High-fat western diet consumption exacerbates silica-induced pulmonary inflammation and fibrosis

炎症与纤维化

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Adipose tissue (AT), an endocrine organ, plays a central role in maintenance of whole-body energy homeostasis through its release of adipokines. Obesity, affecting over 40% of American adults, disrupt

Hypothalamic Microglia Activation is Associated with High Fat Diet-Induced Obesity and Metabolic Dysfunction in Mice

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