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One-Pot Transition-Metal-Free Synthesis of Dibenzo[b,f]oxepins from 2‑Halobenzaldehydes

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Figshare2016-02-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/One_Pot_Transition_Metal_Free_Synthesis_of_Dibenzo_i_b_i_i_f_i_oxepins_from_2_Halobenzaldehydes/2480872
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A one-pot transition-metal-free, base-mediated synthesis of dibenzo[b,f]oxepins was developed. The reaction of 2-halobenzaldehydes with (2-hydroxyphenyl)acetonitriles proceeds via a sequential aldol condensation and intramolecular ether formation reaction in the presence of Cs2CO3 and molecular sieves in toluene.
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2016-02-20
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