One-Pot Transition-Metal-Free Synthesis of Dibenzo[b,f]oxepins from 2‑Halobenzaldehydes
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A one-pot transition-metal-free, base-mediated synthesis of dibenzo[b,f]oxepins was developed. The reaction of 2-halobenzaldehydes with (2-hydroxyphenyl)acetonitriles proceeds via a sequential aldol condensation and intramolecular ether formation reaction in the presence of Cs2CO3 and molecular sieves in toluene.
创建时间:
2016-02-20



