PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03A11 from the F2X-Universal Library

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03A11 from the F2X-Universal Library Descriptor: A1 cistron-splicing factor AAR2, N-methyl-1-{(1S,2R)-2-[(1,2,4-triazolidin-1-yl)methyl]cyclohexyl}methanamine, Pre-mRNA-splicing factor 8 Authors: Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. Deposit date: 2022-08-26 Release date: 2022-11-02 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022PanDDA分析工作组提交的数据集——Aar2/核糖核酸酶H（RNaseH）与F2X通用文库（F2X-Universal Library）片段P03A11的复合物。描述符：A1顺式剪接因子AAR2、N-甲基-1-{(1S,2R)-2-[(1,2,4-三唑烷-1-基)甲基]环己基}甲胺、前mRNA剪接因子8。作者：Barthel, T.、Wollenhaupt, J.、Lima, G.M.A.、Wahl, M.C.、Weiss, M.S.。提交日期：2022-08-26；发布日期：2022-11-02；最后修改日期：2024-05-22。研究方法：X射线衍射（分辨率1.56埃）。引用文献：《大规模晶体学片段筛选加速化合物优化并鉴定潜在蛋白质-蛋白质相互作用位点》，《药物化学杂志（J. Med. Chem.）》，第65卷，2022年