Multi-omics and genome-scale modeling reveal a metabolic shift during C. elegans ageing

We conducted a time series of transcriptomics measurements during normal ageing in C. elegans in two non-reproductive strains (fem and gem) during normal ageing (days 1 to 10 of adulthood) and used this together with a multi-omics modelling pipeline to explore the changes that take place due to ageing. Two strains and several time points with three replicates per strain and time point.