Neoplastic transformation in bystander cells expressed as number of foci/flask or flasks without foci.

Spontaneous neoplastic transformation in the progeny of bystander C3H 10T½ MEFs that had been in co-culture, 10 population doublings earlier, with MEFs irradiated with 1 GeV/nucleon iron ions or with sham-irradiated MEFs. The data of 3 independent experiments were summed and analyzed in terms of the number of foci per flask or the number of flasks without foci.aData from each independent experiment are shown separately.bP values are calculated with a Fisher's exact test based on comparing the total number of events per flask, when bystander cells were co-cultured with irradiated cells, with the corresponding data from respective control.