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B cell-intrinsic STAT3-mediated interferon suppression during murine gammaherpesvirus 68 infection revealed through in vivo competition model.[ccbr1030_Stat3_2021]

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP428269
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RNA-sequencing from sorted B cells of d16 infected mixed bone marrow chimeras. Non-GC, GC uninfected, and GC infected samples of STAT3 WT and STAT3 KO B cells from 3 independent mixed bone marrow chimera experiments. Overall design: 25,000 STAT3 WT or STAT3 KO non-germinal center and germinal center B cells, of which GC cells were both uninfected and infected with MHV68 (YFP+) were sorted, followed by RNA sequencing. Three independent experiments, infected GC samples had 2x samples per expeirment, for a total of 24 samples (3 of which failed QC).
创建时间:
2024-02-27
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