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Single-cell profiling of penta- and tetradactyl mouse limb buds identifies early mesenchymal progenitors required to specify digit numbers and asymmetry

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NIAID Data Ecosystem2026-05-02 收录
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Developing limb cells are heterogeneous. We used single cell RNA sequencing to compare a wildtype limb to two different Grem1 tetradactyl mutants at E10.75 and found differences in populations. Limbs were chopped from E10.75 mouse embryos. Cells were dissociated and used to prepare libraries

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2025-02-25
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